Details
The process are simple, but it's still difficult. First, we have to draw the main lines or the edges of the portrait.
Then we have to choose colors for what we gonna paint and of course for the background. But colors go with light. We have to pay attention to the light, specially to the direction of the light.
After that, we have just to choose a brush, to configure it to have something true...and with the graphic tablet, just paint like you would do on a paper. I often change the size, I mix colors between us to make more "true"...and finally, it's just the practice I think.